What is the best type of hybrid weed for nausea relief?

Indica-dominant hybrids quell nausea while preserving mental clarity. These carefully crafted hybrid strains deliver deep physical comfort and calm nausea from chemotherapy, digestive conditions, or motion sickness without the excessive sedation of pure indicas. 

Feeling queasy? Bliss gummies pack 5 mg of THC and 5 mg of CBD for a balanced, feel-good experience you’ll love. Experience the balance of relief with our precisely microdosed THC edibles.

Is indica or sativa better for nausea relief?

All weed strains come from two primary families: indica and sativa.

1. Indica plants produce high levels of sedating compounds that create powerful physical effects: deeply relaxing muscles, calming the body, and stimulating appetite.
2. Sativa plants affect the mind rather than the body. Their distinct compounds create energizing, cerebral effects that enhance mood and mental clarity. This stimulating nature means they typically offer less physical relief than indicas and can sometimes intensify bodily awareness and discomfort.

Indicas show stronger nausea-fighting properties through their physical relaxation and digestive comfort, while sativas might increase discomfort due to their energizing effects. But pure indicas often prove too sedating for regular use, despite their excellent ability to manage severe symptoms.

This is why balanced, indica-dominant hybrids are your best bet. With a ratio of 60–70% indica genetics, these strains retain robust nausea-fighting properties with enough sativa to keep you alert. The result is nausea relief without the heavy sedation that allows you to function normally throughout your day.

What cannabinoids help with nausea?

The specific mix of cannabinoids in hybrid strains matters more than total THC or CBD content alone. Tetrahydrocannabinol (THC) and cannabidiol (CBD) team up against nausea. Microdoses of THC provide immediate nausea symptom relief while CBD helps sustain those benefits longer-term. Indica-dominant hybrids with a 2:1 THC to CBD ratio are most effective because this balance maximizes anti-nausea properties while minimizing the potential psychoactive effects of THC.

Beyond THC and CBD, other minor cannabinoids found in indica-leaning strains play supporting roles in alleviating strong feelings of nausea.

• According to a 2024 study, THC activates CB1 cannabinoid receptors in stomach cells to reduce histamine release and stomach acid production which can trigger nausea and digestive discomfort.
• THC soothes bouts of nausea by decreasing dopamine signaling in the chemoreceptor trigger zone. This makes the brain's vomiting center less responsive to nausea stimuli.
• CBD enhances the body's natural endocannabinoid system (ECS), particularly anandamide, which activates CB1 and CB2 receptors for comprehensive nausea relief.
• CBD also activates specific serotonin receptors (5-HT1A) in the brain that regulate nausea responses, while also modulating digestive hormones such as ghrelin and motilin.
• Cannabigerol (CBG) targets nausea by blocking serotonin release similar to THC. It's most effective for motion-related nausea and stomach discomfort.
• Cannabichromene (CBC) enhances the anti-nausea effects of THC and CBD while reducing intestinal inflammation.
• Cannabinol (CBN) works on multiple levels: preventing nausea and appetite loss and reducing inflammation that can trigger digestive distress.

Indica-dominant hybrids contain an optimal balance of cannabinoids for nausea relief: 15–20% THC and 7–10% CBD, plus a spectrum of supporting compounds that add layers of relief through their distinct properties.

The right cannabinoid profile makes all the difference for effective nausea relief. Pure indica strains often have excessive THC, which may cause unwanted psychoactive effects, while pure sativas lack sufficient CBD to combat nausea. Hybrids create a precise balance of THC, CBD, and terpenes for relief without sedation or discomfort. This synergistic relationship creates a powerful entourage effect that targets multiple aspects of nausea. 

Our entourage effect gummies deliver the full benefits of hybrid cannabis for nausea relief through a carefully curated blend of cannabinoids. Balanced THC and CBD in these gummies provide anti-nausea relief with reduced side effects.

Try our Relax Plus edibles with 5 mg of THC and 25 mg of CBD. They work together to relieve nausea and provide natural relaxation, so you can feel at ease all day.

“I take a half of a gummy in the morning, and it makes me calm and able to handle whatever comes my way. I will continue to order this wonderful product.”

—Tina M.

Best cannabis terpenes for nausea

Balanced hybrid strains excel at nausea relief because of the cannabinoids and terpene blend. Cannabis terpenes are aromatic molecules that work synergistically with THC, CBD, and other compounds to enhance the anti-nausea effects.

These five terpenes play essential roles in how indica-dominant strains fight nausea: 

1. Limonene delivers fast-acting relief from queasiness and nausea while boosting mood and maintaining energy levels.
2. Pinene acts as a powerful anti-inflammatory throughout the digestive system and reduces inflammation-related nausea while keeping your mind sharp and alert.
3. Caryophyllene is the only terpene that directly activates the body's cannabinoid receptors and relieves digestive discomfort and gut inflammation.
4. Myrcene relaxes the entire body. It eases the muscle tension and physical stress that often trigger or intensify nausea while promoting healthy digestive function.
5. Linalool works on physical and mental levels to calm anxiety that can cause nausea. At the same time, this terpene soothes stomach discomfort, especially in those dealing with stress-induced symptoms.

The complex terpene profiles of hybrid strains deliver comprehensive symptom relief while keeping you functional throughout the day. 

What strain of weed is best for nausea?

Through decades of careful breeding and extensive patient feedback, certain hybrid strains have proven exceptionally effective at relieving nausea. These carefully crafted varieties contain precisely balanced cannabinoid ratios and targeted terpene profiles that provide fast-acting, sustainable relief.

Here are the most effective hybrid strains for comprehensive relief from nausea:

1. Blue Dream delivers a balanced experience with uplifting effects. This slightly dominant sativa hybrid features high levels of terpenes that quickly settle stomach discomfort while maintaining energy and focus throughout the day.
2. Girl Scout Cookies provides powerful antiemetic properties through its indica-dominant profile and rich caryophyllene content. It delivers therapeutic effects without excessive sedation.
3. OG Kush is a strong indica-leaning hybrid with high levels of nausea-relieving terpenes. It calms physical tension, upset stomach, and anxiety that triggers or worsens nausea.
4. Wedding Cake is a potent strain among indica-dominant hybrids that provides comprehensive relief from severe nausea through its balanced terpene profile while preserving mental clarity.
5. Zkittlez brings a moderately indica-leaning profile with an exceptional concentration of calming compounds for quick relief particularly suited for stress-related nausea.
6. Gelato achieves an almost perfect hybrid balance, providing soothing effects through its unique terpene combination. Its rich array of compounds reduces inflammation and maintains functionality throughout the day.

With nama™, there’s no need to stick to just one strain. You’ll experience the ultimate blend of hybrid strains because our low-dose edibles and THC-infused beverages provide soothing and balanced nausea relief. 

Our cannabis products harness the anti-nausea power of all six (and more) strains to deliver microdoses of just 2–10 mg of THC per edible. This precise dosing allows you to enjoy the benefits without feeling overwhelmed, keeping you clear-headed, comfortable, and in control. 

If you’re a newbie to hybrid weed, start low with our Energy gummies. They pack only 2.5 mg of THC per serving balanced by 5 mg of CBD to keep you energized, focused, and nausea-free. 

“I love these. My favorite by far. Just one and I'm able to shut my brain up long enough to get things done. And the flavor is wonderful…”

—Meghan

What are the best hybrid edibles for nausea?

Our hybrid cannabis edibles are expertly crafted to provide precise and effective nausea relief. Made from premium, non-GMO American hemp, every product is 100% American-made and rigorously tested for quality. By partnering with small organic farms in Colorado and New Jersey, we deliver a clean and reliable experience you can trust.

Here are some of our top hybrid edibles for combating chronic nausea:

• Bliss gummies (5 mg THC, 5 mg CBD) deliver fast-acting nausea relief with a balanced ratio of THC and CBD. This blend calms your stomach while lifting your mood, providing effective relief without causing excessive sedation or stimulation.
• Energy gummies (2.5 mg THC, 5 mg CBD) pair a mild amount of THC with a higher dose of CBD to ease nausea while keeping you alert and energized. These daytime relief gummies also contain B12 and L-theanine for focus and mental clarity.
• Relax Plus gummies (5 mg THC, 25 mg CBD) offer soothing relief from nausea and anxiety, especially when stress exacerbates your symptoms. The higher CBD content amplifies anti-emetic properties while reducing the potential side effects of too much THC.
• Buzz Drops™ (2.5 mg THC, 2.5 mg CBD per dropper) let you create therapeutic nausea-relief beverages with ease. Our liquid drops mix seamlessly into sparkling water, juice, or mocktails and are the essential part of our delicious buzztails™. With quick absorption and precise dosing control, they provide fast relief that calms your stomach without clouding your mind.

Our hybrid gummies and cannabis-infused drinks address a range of discomforts (nausea, stress, aches, or sleep issues) without interfering with your daily routine. Whether you’re relaxing after a long day or need fast relief while on the go, our products offer calm and comfort at your fingertips. 

Simply pop a gummy or mix a few drops into your favorite drink to feel your best. Order from nama today, and feel the quality difference.

Resources

Hornby, P. J., & Prouty, S. M. (2004). Involvement of cannabinoid receptors in gut motility and visceral perception. British Journal of Pharmacology, 141(8), 1335. https://doi.org/10.1038/sj.bjp.0705783

Further reading

Is hybrid or sativa better for sleep?

How does hybrid cannabis reduce inflammation?

Can cannabis boost chemotherapy treatment?

Why is microdosing weed better for mental health?

The most effective strains for anxiety and OCD

What are the negative effects of hybrid weed?

Can hybrid cannabis help my arthritis?

What is the best type of weed for chronic fatigue?

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