Are Buzz Drops™ hard on the liver?

Buzz Drops™ allow you to enjoy a mild buzz that is kind to your liver. Each dropper contains precise microdoses of THC and CBD for a controlled and enjoyable experience without the liver-damaging effects of alcohol.

Read on to see what makes our low-dose THC beverages gentle on the liver and a healthier alternative to booze.

What are Buzz Drops™?

Buzz Drops™ are liquid cannabis tinctures that contain 2.5 mg of THC (tetrahydrocannabinol) and 2.5 mg of CBD (cannabidiol). This ultra-low amount of cannabinoids ensures you get the right amount every time without the harsh side effects often associated with weed. Unlike high doses, THC microdoses provide therapeutic and medicinal benefits.

And unlike alcohol, you won’t feel intoxicated, impaired, or groggy. You can infuse any beverage with low-dose liquid drops to create mouth-watering buzztails™ and enjoy an alcohol alternative that supports your well-being.

Thanks to their water-soluble formula, Buzz Drops™ take around 10 minutes to kick in. They don't wear off quickly like other unhealthy fast-acting consumption methods. The effects of Buzz Drops™ last up to four hours for most people. Thanks to the efficient absorption of water-soluble cannabinoids, our liquid cannabis beverages provide a more consistent and sustained cannabis experience. 

Whether you need to unwind or boost your focus, Buzz Drops™ provide a reliable, extended effect without the crash.

How do THC and CBD affect the liver?

Cannabis compounds are metabolized in the liver through enzymes in the cytochrome P450 system. These enzymes process drugs, toxins, and cannabinoids by breaking them down into more easily excreted compounds. Metabolism affects how long cannabinoids remain active in the body. In high doses, the metabolization of THC and CBD elevates liver enzymes and puts a temporary strain on the organ. 

The liver contains cannabinoid receptors CB1 and CB2. They are part of the body's endocannabinoid system (ECS), a complex communication network throughout our body. It helps keep bodily functions in balance, from mood and appetite to inflammation and pain. In the liver specifically, this system helps control metabolism and energy.

THC and CBD interact with the receptors in the ECS to alter liver metabolism and inflammation. For example, activating CB1 receptors increases fat storage in the liver, while CB2 activation reduces inflammation. Cannabis affects liver health depending on how much you use—small amounts might be helpful, while large amounts could harm. 

Here’s what we know about how THC and CBD interact with the liver:

• Delta 9 THC is the primary psychoactive compound in cannabis. The liver’s response to THC is dose-dependent: when consumed in large amounts, THC puts stress on the liver, but smaller, therapeutic amounts provide benefits without causing significant liver strain.
• At lower therapeutic doses, CBD may reduce lipid accumulation in liver cells. This could prevent or treat fatty liver disease (steatosis), a condition where too much fat builds up in the liver and leads to inflammation and damage. Mboumba Bouassa, et. al. proved this anti-steatosis effect in both cell cultures and obese mice.
• THC may have the opposite effect on lipid metabolism. McIntosh et al. (2018) found that THC can increase levels of endocannabinoids in the liver, exacerbating fatty liver disease. This effect appears to be dose-dependent. Lower doses of THC do not cause the same harmful effects as higher doses.
• CBD has antioxidant and anti-inflammatory properties in the liver at lower doses. A 2017 study posits that it can reduce alcohol-induced liver damage in mice by decreasing inflammation, oxidative stress, and fat accumulation in the liver. 

A 2023 study published in the Canadian Liver Journal explains that, in people with liver disease, cannabis could have stronger effects and stay in the system longer, potentially amplifying both its therapeutic and harmful impacts on the liver and overall endocannabinoid system.

These findings suggest that cannabis offers therapeutic benefits for liver health when used in lower, controlled doses. Low-dose cannabis may even fight liver cancer and lower cancer risk. ElTelbany, et. al. found that patients with a history of cannabis use are 55% less likely to develop liver carcinoma than non-cannabis users—as long as you stick to the lower, therapeutic amounts as found in our Buzz Drops™.

Whether you're infusing your favorite sippers with Buzz Drops™ or exploring our delicious THC gummies, you can relax knowing you're consuming a product that’s both effective and liver-friendly.

Can you say the same about alcohol?

"These drops are the perfect replacement for my dry January. In fact, this may become a dry 2024! The hit is smooth and steady, just like having a light wine buzz. These don't make me sleepy or feel head in the clouds—just a nice, calm, happy little buzz…"

—Amber

The benefits of Buzz Drops™ for the liver

We've carefully crafted our Buzz Drops™ and other cannabis products to stay below the 10 milligrams of THC threshold so you can experience the benefits while minimizing the issues associated with higher cannabis consumption. 

Low doses of THC and CBD do not cause significant stress or damage to the liver. In fact, sipping our low-dose buzztails™ infused with Buzz Drops™ offers refreshment and a mild buzz while potentially protecting your liver and supporting your body's natural defense systems. 

The benefits of Buzz Drops™ for the liver include: 

1. Reduced inflammation. Buzz Drops™ contain two major cannabinoids with potent anti-inflammatory properties. A 2009 study found that THC activates CB2 receptors to reduce inflammation and fibrosis, suppresses pro-inflammatory cytokines, and aids in the mitigation of liver damage. In a 2022 study, CBD improved glucose tolerance, reduced inflammatory responses, and partially mitigated microbiome dysbiosis in a non-alcoholic fatty liver disease (NAFLD) mouse model.
2. Reduced stress. Chronic stress can negatively impact the liver, contributing to or exacerbating conditions such as fatty liver disease. A 2019 review discusses the potential roles of psychological stress in the pathogenesis of NAFLD, stating that psychological stress can increase inflammation and worsen metabolic disorders. Buzz Drops™ can manage anxiety and stress, reducing the strain on your liver.
3. Improved sleep. Quality sleep is crucial for liver regeneration and detoxification. By promoting better sleep, Buzz Drops™ aid in the liver’s ability to repair and detoxify itself, enhancing overall liver function.
4. Pain management. Chronic liver conditions can cause discomfort, but Buzz Drops™ contain small amounts of analgesic THC and CBD. Cannabinoids interact with the ECS to modulate pain perception and inflammation. 
5. Reduced nausea. People who deal with chronic liver issues or are undergoing treatments often experience bouts of nausea and vomiting. THC acts as an antiemetic: it alleviates nausea. THC reduces nausea by suppressing serotonin signals that trigger vomiting and inhibiting the vomiting center in the brainstem to make it less sensitive to nausea triggers. 

When consumed in moderation, our low-dose cannabis beverages offer liver benefits. We can’t think of a better way to reap those benefits than with a chilled glass of our blueberry thyme mocktail, a cannabis twist on the classic mojito, or any other mouth-watering mocktail from our recipe book. 

With our guide on how to create stunning craft mocktails, you’ll get into the weeds in no time. If you don’t have time for mixing up drinks (which literally takes a few minutes), you can use our Buzz Drops™ to infuse any drink—your morning cup of coffee or tea, your favorite soft drink, and even a glass of milk. 

Why are Buzz Drops™ the best replacement for alcohol?

Alcohol is extremely damaging, not just to the liver but to overall health. It causes high blood pressure, heart disease, stroke, and an increased risk of cancer. The potentially life-threatening side effects of heavy alcohol intake include alcohol poisoning, addiction, and severe withdrawal symptoms. 

Here are the main reasons why our Buzz Drops™ are the perfect alcohol replacement:

1. Buzz Drops™ contain lower doses of THC and CBD, which minimizes liver strain, unlike the higher toxicity levels of alcohol. 
2. Alcohol is a risk factor for liver diseases such as cirrhosis and hepatitis, but the cannabinoids in Buzz Drops™ have not been shown to cause such conditions. 
3. Alcohol is also a known risk factor for liver and other types of cancer. It promotes mutations in liver cells and compromises the liver's ability to detoxify the body. Buzz Drops™ do not carry the same carcinogenic risks. In fact, microdosing cannabis may fight many types of cancer. 
4. Buzz Drops™ are free from ethanol, the primary agent in alcoholic beverages that contributes to liver damage. We only use water-soluble hemp-extracts of THC and CBD and purified water. 
5. THC and CBD both have anti-inflammatory properties that help reduce inflammation in the liver (often caused by heavy drinking).
6. Buzz Drops™ contain fewer calories than alcoholic beverages. Excessive caloric intake from alcohol can contribute to liver fat accumulation and increase the risk of fatty liver disease.
7. Alcohol metabolism produces acetaldehyde, a toxic byproduct that damages liver cells. The metabolism of cannabis compounds found in Buzz Drops™ does not produce acetaldehyde.
8. Heavy alcohol consumption often leads to painful hangovers that strain the liver because it has to work overtime to process toxins from alcohol. Buzz Drops™ offer a mild buzz without the next-day hangover, sparing your liver from additional stress.
9. Alcohol has a high potential for addiction, which can lead to or exacerbate existing liver problems. Buzz Drops™ is a low-risk alternative with minimal addiction potential.

Do you need more proof that our cannabis beverages are the best, cleanest, guilt-free alternative to alcohol? 

If you’ve never used Buzz Drops™ before and you fear you wouldn’t know how, don’t worry—our liquid cannabis drops are pretty straightforward. All you need is your drink and a bottle of Buzz Drops™. Within 10 to 20 minutes, you’ll start to feel the calming effects of CBD and the mellow buzz of THC that no type of alcoholic drink can achieve. 

“Just ordered my 3rd bottle of buzz drops. This has completely replaced my nighttime glass of wine. Gives you a nice, relaxed buzz while still being able to function. Hangovers are history with this stuff. Sleep has improved and I wake up feeling refreshed and ready to take on the day… I use 2—3 droppers depending on how chill I want my evening to be. Buy it! Give up those hangovers and extra calories from booze.”

—Gina K.

The potential side effects of Buzz Drops™

Like any cannabis product, excessive doses of Buzz Drops™ can lead to side effects. Our low-dose approach helps users experience the therapeutic benefits without adverse effects. 

The standard recommended dose is two full droppers, which contain 5 mg of THC and 5 mg of CBD. You can start with one full dropper or even half if you’re worried about the fast-acting properties or have never experimented with liquid cannabis before. 

Some experienced cannabis users choose to double or triple their dose to experience mild euphoria and a light buzz without significant side effects. People generally have different tolerances and feel the effects of cannabis at different dosages. If you go overboard with your dose of Buzz Drops™, you may encounter some of the following side effects:

• Dry mouth
• Dry eyes
• Drowsiness
• Increased appetite
• Mild anxiety or paranoia
• Dizziness
• Impaired coordination
• Short-term memory impairment

These side effects are mild and subside within a few hours. Even if you consume a large amount of Buzz Drops™, the worst outcome is temporary discomfort such as intense dizziness or paranoia without any lasting harm.

The same goes for our THC gummies. Believe us when we tell you that we’ve mastered the craft of creating microdosed cannabis products so you can reap the benefits of weed without experiencing intense psychoactivity or other side effects. 

Order our Bliss Delta 9 edibles with a balanced 5 mg of THC and CBD and experience a blend of relaxation and clarity packed in a delicious honeydew gummy form. If you’re up for something more potent but equally juicy, our Euphoria THC gummies are the way to go. 

Where to buy Buzz Drops™

We exclusively produce and sell Buzz Drops™ because we want you to receive the highest quality product every time. Our rigorous lab tests demonstrate our commitment to purity, allowing you to see the results firsthand. Our scientists extract THC and CBD from 100% organic, non-GMO, American-grown hemp and craft it into our uplifting cannabis drops. 

With our personalized Buzz Drops™ subscription and automated deliveries straight to your door, you’ll be saving time and hassle and never worrying about running low or reordering again.

Resources

Mboumba Bouassa, R., Sebastiani, G., Di Marzo, V., Jenabian, M., & Costiniuk, C. T. (2021). Cannabinoids and Chronic Liver Diseases. International Journal of Molecular Sciences, 23(16), 9423. https://doi.org/10.3390/ijms23169423

McIntosh AL, Martin GG, Huang H, Landrock D, Kier AB, Schroeder F. Δ9-Tetrahydrocannabinol induces endocannabinoid accumulation in mouse hepatocytes: antagonism by Fabp1 gene ablation. J Lipid Res. 2018 Apr;59(4):646-657. doi: 10.1194/jlr.M082644. Epub 2018 Feb 5. PMID: 29414765; PMCID: PMC5880504.

Wang, Y., Mukhopadhyay, P., Cao, Z., Wang, H., Feng, D., Haskó, G., Mechoulam, R., Gao, B., & Pacher, P. (2017). Cannabidiol attenuates alcohol-induced liver steatosis, metabolic dysregulation, inflammation and neutrophil-mediated injury. Scientific Reports, 7(1), 1-12. https://doi.org/10.1038/s41598-017-10924-8

Zhu, J., & Peltekian, K. M. (2018). Cannabis and the liver: Things you wanted to know but were afraid to ask. Canadian Liver Journal, 2(3), 51-57. https://doi.org/10.3138/canlivj.2018-0023

ElTelbany A, Khoudari G, Al-Khadra Y, McCullough A, Alkhouri N. Lower Rates of Hepatocellular Carcinoma Observed Among Cannabis Users: A Population-Based Study. Cureus. 2022 Apr 28;14(4):e24576. doi: 10.7759/cureus.24576. PMID: 35651376; PMCID: PMC9138632.

Gorelick, J., Assa-Glazer, T., Zandani, G., Altberg, A., Sela, N., Nyska, A., & Madar, Z. (2022). THC and CBD affect metabolic syndrome parameters including microbiome in mice fed high fat-cholesterol diet. Journal of Cannabis Research, 4(1). https://doi.org/10.1186/s42238-022-00137-w

Nagarkatti, P., Pandey, R., Rieder, S. A., Hegde, V. L., & Nagarkatti, M. (2009). Cannabinoids as novel anti-inflammatory drugs. Future Medicinal Chemistry, 1(7), 1333. https://doi.org/10.4155/fmc.09.93

Zhang, S., Ma, C., Wang, X., Wang, Q., Song, W., Li, C., Zhai, C., Qi, Y., Fan, S., & Cheng, F. (2019). Impact of chronic psychological stress on nonalcoholic fatty liver disease. https://www.semanticscholar.org/paper/Impact-of-chronic-psychological-stress-on-fatty-Zhang-Ma/13321d2bf0741c0d5779662297e169a584e27c0e

Further reading

Are Buzz Drops™ legal in the US?

How do Buzz Drops™ work?

What should I use Buzz Drops™ for?

Can Buzz Drops™ make you anxious?

Will Buzz Drops™ make me fail a drug test?

Will Buzz Drops™ make me hungry?

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