What is phytol?

Phytol contributes a delicate, fresh-cut grass aroma to many hybrid weed strains. It may be a lesser-known terpene found in cannabis, but this aromatic compound packs calming and anxiety-reducing properties.

Straddling the line between sativa and indica, hybrid cannabis varieties deliver a well-rounded experience that harnesses the strengths of both worlds and their rich cannabinoid and terpene profiles. 

We've infused our low-dose THC edibles with phytol to enhance their therapeutic effect and appeal.

Phytol cannabis terpene

Phytol is a diterpene alcohol with the molecular formula C20H40O. It participates in the synthesis of vitamins E and K. In cannabis, phytol contributes to the plant's complex aroma profile and therapeutic benefits. Beyond cannabis, phytol occurs in green tea, some vegetables, and even certain essential oils. 

Like other terpenes, phytol is a volatile compound; it readily evaporates at room temperature. This volatility is why you might detect phytol’s subtle, fresh-cut grass scent when near certain cannabis strains.

Phytol contributes to the entourage effect. The entourage effect is a theory that cannabinoids, terpenes, and other cannabis compounds work synergistically to enhance the plant's overall effects. Terpenes interact with cannabinoids to modulate their effects on the body's endocannabinoid system (ECS). This complex cell-signaling system regulates nearly every physiological process, including mood, sleep, appetite, inflammation, and pain sensation.

Phytol's sedative properties might enhance the relaxing effects of some cannabinoids, while its anti-inflammatory capacity complements the pain-relieving properties of others. The intricate interplay between phytol and other compounds contributes to the unique effects and therapeutic potential of cannabis.

To fully harness these potential health benefits, many enthusiasts are turning to microdosing, a practice of consuming small, precisely measured amounts of cannabis regularly. This way, you can experience the subtle, beneficial effects of phytol and other compounds without overwhelming the system, achieving more balanced and sustainable results.

What does phytol smell like?

Phytol has a subtle and distinctive earthy and grassy aroma. Its smell reminds many users of fresh-cut grass or newly mown lawns. Some people detect faint floral undertones in phytol. It's also described as having a delicate tea-like scent, similar to green tea.

Its taste is mild and slightly bitter. In cannabis strains where phytol is present in higher concentrations, it contributes to a subtle, green flavor.

Phytol's characteristic smell and taste also contribute to the flavor profile of:

• Green tea
• Spinach
• Basil
• Beans
• Seaweed
• Jasmine
• Lettuce
• Parsley
• Mint
• Stinging nettle

What are the effects and benefits of phytol?

Phytol has a range of beneficial effects on human health. Its properties hit each user differently, but overall, phytol is associated with:

• Sedative effects: Phytol helps you relax and unwind. Users report feeling calmer and more at ease after consuming cannabis strains high in phytol.
• Anxiolytic properties: If you're dealing with stress or anxiety, phytol offers relief. Its calming effect on the nervous system can quiet racing thoughts or ease tension. Studies show that its anxiolytic effects are mediated through interaction with the GABAergic system and that phytol works similarly to common anti-anxiety medications.
• Anti-inflammatory action: Inflammation is at the root of many health issues. Phytol shows promise in reducing inflammation, benefiting people who struggle with arthritis and skin problems. According to de Moraes, et. al., “phytol has shown antinociceptive and antioxidant activities as well as anti-inflammatory and antiallergic effects.”
• Analgesic effects: Got aches and pains? Phytol’s pain-relieving properties are useful for managing physical discomfort, from headaches to chronic pain.
• Antioxidant properties: Phytol protects your cells from oxidative stress. It neutralizes harmful free radicals in your body, reducing the risk of chronic diseases and supporting cellular health.
• Mood regulation: Phytol may regulate mood by interacting with the brain's neurotransmitter systems. Its calming and anxiolytic properties stabilize emotional states, easing symptoms of anxiety and promoting a more balanced mood. 
• Possible neuroprotective effects: Phytol might protect your brain cells. Its antioxidant and anti-inflammatory properties in the nervous system could slow down neurodegenerative processes, boosting brain health and cognitive function as we age.
• Mild muscle relaxant effects: If you're feeling tense or dealing with muscle spasms, phytol's muscle-relaxing properties might provide relief. 
• Potential appetite stimulation: Some users report increased hunger after consuming phytol-rich cannabis. Phytol contributes to the appetite-stimulating effects of cannabis. 
• Possible anticonvulsant: Phytol may manage seizures. Its interaction with the GABAergic system suggests it could benefit patients with epilepsy and other seizure disorders.
• Promising anti-tumor activity: Phytol might fight cancer by interacting with certain receptors in our cells that reduce inflammation and slow tumor growth. Indian researchers posit that in synergy with other terpenes such as bisabolol, phytol enhances anticancer effects by promoting apoptosis and reducing cancer cell viability (That’s the entourage effect.).

A 2020 study highlights phytol’s potential in fighting cancer, but warns that it may be a bit of a double-edged sword; while small amounts could be beneficial, too much may harm healthy cells. This is exactly why microdosing cannabis is such a game-changer.

Microdosing lets you tap into cannabis's benefits with greater precision, minimizing unwanted side effects while maximizing therapeutic potential.

With our Relax Plus gummies, you're getting a carefully balanced blend of cannabinoids (5 mg of THC and 25 mg of CBD) and a rich terpene profile that includes just the right amount of phytol. Our formulation allows you to find that sweet spot for relaxation and wellness while you enjoy the fresh watermelon flavors.

“I took my first Relax Plus gummy last evening and not only was it delicious, it calmed me down! My evening was peaceful and I slept like a baby…”

—Barbara R.

Side effects of phytol

Phytol is often used in essential oils, cosmetics, and even some medicinal products, which makes it safe and well-tolerated at low doses. Excessive consumption or exposure may lead to some side effects such as:

• Skin irritation: Prolonged or excessive topical application of phytol-containing products can cause skin redness, itching, or rash.
• Respiratory issues: Inhalation of high concentrations of phytol may lead to respiratory irritation, coughing, or shortness of breath.
• Gastrointestinal discomfort: Oral ingestion of large doses of phytol might cause nausea, vomiting, or stomach pain.
• Central nervous system effects: At very high doses, phytol may cause dizziness, headaches, or drowsiness.
• Allergic reactions: Some people may experience allergic reactions, including hives or swelling, particularly if they are sensitive to phytol or related compounds.

Each person reacts to phytol and other cannabis compounds differently. If you’re starting with cannabis for the first time, go slow and start with a small amount to test the waters.

Is phytol toxic?

Phytol can be toxic in two situations:

1. When exposed to excessive amounts: Large doses can cause cytotoxicity, meaning they can damage or kill cells. The toxicity is dose-dependent, so the risk increases with higher amounts. The levels of phytol typically found in food or microdosed cannabis products fall well below this toxic threshold.
2. When inhaled: Phytol poses significant risks when inhaled, especially when used as a thinning agent in vaping products. Research on rats demonstrated severe pulmonary injury from inhaled phytol, including tissue degeneration, necrosis, edema, hemorrhage, and inflammation in the lungs. Health experts strongly advise against using vaping products that contain phytol.

In oral cannabis products, the body processes phytol differently than when inhaled. When you stick to microdosing and our cannabis edibles or low-dose THC beverages, you can reap the benefits of phytol and other terpenes and cannabinoids without risking toxicity or lung damage. 

Enjoy the enhanced experience of cannabis in a refreshing and responsible way with every sip of our buzztails™. Take your favorite mocktail or a soft drink, add a dropper or two of our Buzz Drops™, and create a stunning THC mocktail that elevates your mood while protecting your lungs and cells. 

“Just ordered my 3rd bottle of buzz drops. This has completely replaced my nighttime glass of wine. Gives you a nice, relaxed buzz while still being able to function…”

—Gina K.

Learn how to craft booze-free cannabis drinks for mild euphoria and deep relaxation.

Which strains are rich in phytol?

Phytol is a terpene commonly found across various cannabis strains, including sativa, indica, and hybrids. Some of the most popular sativa strains rich in phytol are:

• Durban Poison
• Jack Herer
• Green Crack

Indica strains with a high phytol profile include: 

• Granddaddy Purple
• Northern Lights
• Bubba Kush

While indica and sativa varieties offer their own therapeutic and recreational benefits, the benefits of hybrid weed surpass both. Phytol is a regular terpene in the following hybrid strains:

• OG Kush
• Girl Scout Cookies (GSC)
• Blue Dream

With nama™, you don't have to choose between strains. Our products balance cannabinoids and terpenes from hybrid varieties to produce a well-rounded experience and capture the full potential of cannabis. Try our Energy Delta 9 gummies with 2.5 mg of THC and 5 mg of CBD to experience a perfectly balanced, soothing effect of phytol, uplifting linalool, gentle myrcene, and other aromatic terpenes.

The best hybrid edibles with rich terpene profile

Looking for hybrid cannabis products rich in beneficial terpenes, flavonoids, and other cannabis compounds? Look no further than nama. We specialize in premium cannabis edibles that deliver a wide range of benefits from carefully selected cannabinoids and terpenes. 

Our gummies and THC mocktails offer the perfect balance of effects, providing a soothing and relaxing experience. We combine calming and uplifting terpenes with the therapeutic potential of THC and CBD to create the highest-quality edibles. Whether you're seeking stress relief or better sleep, our phytol-rich formulations help you unwind and find balance.

You can purchase the best edibles right here at nama. 

Resources

Costa, J. P., De Oliveira, G. A. L., De Almeida, A. A. C., Islam, M., De Sousa, D. P., & De Freitas, R. M. (2014). Anxiolytic-like effects of phytol: Possible involvement of GABAergic transmission. Brain Research, 1547, 34-42. https://doi.org/10.1016/j.brainres.2013.12.003

Costa, J. P., G. Junior, A. L., Freitas, R. M., Allegretti, S. M., & S. Pinto, P. L. (2013). Phytol, a Diterpene Alcohol from Chlorophyll, as a Drug against Neglected Tropical Disease Schistosomiasis Mansoni. PLoS Neglected Tropical Diseases, 8(1). https://doi.org/10.1371/journal.pntd.0002617

Bobe, G., Zhang, Z., Kopp, R., Garzotto, M., Shannon, J., & Takata, Y. (2020). Phytol and its metabolites phytanic and pristanic acids for risk of cancer: Current evidence and future directions. European Journal of Cancer Prevention, 29(2), 191-200. https://doi.org/10.1097/CEJ.0000000000000534

Schwotzer D, Gigliotti A, Irshad H, Dye W, McDonald J. Phytol, not propylene glycol, causes severe pulmonary injury after inhalation dosing in Sprague-Dawley rats. Inhal Toxicol. 2021 Jan;33(1):33-40. doi: 10.1080/08958378.2020.1867260. Epub 2021 Jan 13. PMID: 33441006.

Further reading

THC drinks vs. edibles

How to make THC beverages

Side effects of hybrid cannabis strains

Are hybrids uppers or downers?

Our THC gummies that give you energy

How does the hybrid weed trigger the entourage effect?

What is hybrid weed good for?

The best THC microdosing amounts

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