What is bisabolol?

Aug 21, 2024The nama Team
What is bisabolol? - namaCBD

Bisabolol is a gentle, floral-scented cannabis terpene. This aromatic compound offers a range of therapeutic benefits to many cannabis strains including anti-inflammatory, stress-relieving, skin-soothing, and antioxidant properties.

Bisabolol is typically found in indica-dominant hybrid strains. It synergizes with other cannabis compounds to enhance the entourage effect and boost the plant's therapeutic potential.

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What plants is bisabolol found in?

Bisabolol is a naturally occurring terpene commonly used in skincare and wellness products because of its soothing properties, gentle aroma, and therapeutic benefits. While not one of the most abundant terpenes in cannabis, it is still present in many indica-dominant strains, where it contributes to their soothing and relaxing properties. 

Beyond cannabis, bisabolol is found in many plants, including:

  • Chamomile 
  • Basil
  • Holy basil 
  • Rosemary
  • Lavender
  • Cotton
  • Sweet Woodruff 

What does bisabolol taste like?

Bisabolol has a mild, sweet flavor with subtle earthy and herbal undertones. The taste is described as smooth and slightly sweet. Unlike more pungent or spicy cannabis terpenes, bisabolol’s taste is gentle and not overpowering. It adds a soft, sweet note that complements the overall flavor profile of the strain without being too dominant.

This gentle sweetness in taste contrasts its floral aroma, which adds a different layer to the sensory experience.

What is the smell of bisabolol?

Bisabolol carries a light, floral aroma reminiscent of chamomile, with delicate hints of sweetness and a fresh, powdery note. This soothing and gentle scent enhances cannabis strains without overpowering other aromas.

Interestingly, the floral aroma differs from its taste, which is more subtly sweet with earthy undertones. Bisabolol offers a distinct sensory experience through both smell and taste, each complementing the other in unique ways.

When you microdose cannabis, the subtle aromas and flavors of bisabolol and other terpenes won't overpower your senses. Microdosing allows you to enjoy the therapeutic benefits without overwhelming your palate. 

Our THC gummies and cannabis-infused beverages are perfect for a balanced and gentle experience. They contain small amounts of Delta 9 THC and cannabidiol (CBD) for a mild and reliable combination that supports your overall health. 

Effects of bisabolol

Bisabolol’s gentle yet effective properties may enhance your physical and mental well-being. Here are the effects of bisabolol and how it can make you feel:

  • Bisabolol has a calming effect that reduces stress and anxiety. It promotes a sense of relaxation, making it a great addition to strains used for unwinding after a long day.
  • Bisabolol has strong anti-inflammatory properties that reduce swelling and irritation. This soothes skin conditions and relieves discomfort associated with inflammation.
  • It is gentle on the skin and is often used in skincare products to calm redness and irritation.
  • Thanks to its calming effects, bisabolol improves sleep quality. It works well in cannabis strains that help users fall asleep faster and enjoy deeper, more restful sleep.
  • Bisabolol’s soothing nature extends to pain relief. It alleviates discomfort without the need for stronger, more aggressive compounds. Gadotti, et. al. indicate that alpha-bisabolol provides pain relief by inhibiting Cav3.2 T-type calcium channels to reduce pain responses and sensitivity. This makes it effective in treating conditions such as thermal hyperalgesia and neuropathic pain.
  • Bisabolol contains powerful antioxidant properties, fighting free radicals and protecting your body from oxidative stress. This contributes to overall wellness and can slow the aging process of your skin.
  • Bisabolol may have neuroprotective effects. A 2022 study revealed that it protects brain cells from the harmful effects of a substance called amyloid β, which is linked to brain diseases such as Alzheimer’s disease.
  • The gentle floral aroma of bisabolol has aromatherapy benefits. They uplift your mood and reduce tension.

Israeli researchers found that “many terpenes/terpenoids have a therapeutic power in their mixtures with or without phytocannabinoids… α-bisabolol induces apoptosis of malignant tumor cells, cytotoxicity, and antigenotoxicity.” This points to the entourage effect between terpenes and cannabinoids, working synergistically to induce apoptosis in malignant tumor cells. 

Here’s all about the potential benefits of cannabis in fighting cancer.

The entourage effect is the idea that cannabinoids and terpenes work together synergistically to enhance the overall therapeutic effects of cannabis. In hybrid strains, this effect is amplified because the combination of different cannabinoids and terpenes creates a balanced and potent experience.

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Are there side effects of bisabolol?

Bisabolol is safe and is widely used in cannabis and personal care products because of its soothing and therapeutic properties. Like any compound, it may cause side effects in those with sensitivities or allergies. 

The potential side effects of bisabolol include:

  1. Skin irritation: Despite its skin-soothing properties, some people with extremely sensitive skin experience mild irritation, redness, or a burning sensation when using products containing bisabolol.
  2. Allergic reactions: In rare cases, people who are allergic to plants that contain bisabolol, such as chamomile or basil, experience an allergic reaction. 
  3. Contact dermatitis: Bisabolol may cause contact dermatitis. This is more likely to occur if the skin is already compromised or if the concentration of bisabolol in a product is too high.
  4. Eye irritation: If bisabolol-containing products come into contact with the eyes, they may cause irritation, discomfort, and redness.
  5. Gastrointestinal issues: Though uncommon, ingesting bisabolol in high amounts may cause mild gastrointestinal issues, such as nausea or upset stomach.
  6. Headaches: Some people may experience headaches when exposed to high concentrations of bisabolol’s aroma, particularly if they are sensitive to strong scents or terpenes.

The side effects of bisabolol are not common and usually occur only in those with specific sensitivities or when bisabolol is used in large amounts. If you experience any of these symptoms, discontinue use.

You're unlikely to experience side effects from cannabis and its therapeutic compounds if you stick to low doses. Keep your intake moderate and enjoy the benefits without the risk of unwanted reactions.

What strains are high in bisabolol?

Bisabolol is more commonly found in indica-dominant strains, making it ideal for those seeking stress relief and relaxation. 

The following hybrid strains are rich in bisabolol:

  • Harle-Tsu is a balanced hybrid with high CBD levels. It offers mild psychoactive effects and strong therapeutic benefits. Bisabolol in this strain enhances its calming and anti-inflammatory effects.
  • OG Kush is famous for its strong relaxation effects. The presence of bisabolol in this strain amplifies its stress-relieving and soothing properties.
  • Pink Kush is an indica-dominant strain that delivers powerful body relaxation, often used for stress relief and pain management. Bisabolol adds to its calming effects.
  • Master Kush is a classic indica-dominant strain with potent sedative effects. It calms the mind and body and is perfect for nighttime relaxation.
  • Headband is another relaxing indica-dominant hybrid that offers a slight cerebral high. The bisabolol content contributes to its stress-relieving and anti-inflammatory properties.

Hybrid strains offer a balanced experience, blending the soothing properties of indicas with the uplifting effects of sativas. These hybrids often feature complex terpene profiles, allowing bisabolol to contribute to a well-rounded and therapeutic experience through the entourage effect.

At nama™, we've made it easy to find the perfect bisabolol-rich strain. Our cannabis products harness the benefits of hybrids, expertly balancing bisabolol with other terpenes and cannabinoids. This way, you experience bisabolol's unique benefits in a perfectly calibrated blend. 

No need to search for specific strains; we've crafted the ideal bisabolol experience into every product.

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Looking for hybrid cannabis products rich in beneficial terpenes such as bisabolol, limonene, and myrcene? We've got you covered. Our cannabis gummies and drinks offer the perfect balance of effects to provide a soothing and relaxing experience.

We've crafted unique recipes that combine calming terpenes, with a focus on bisabolol for its potential anti-inflammatory and stress-relieving properties. Our products use high-quality, hemp-derived extracts for a consistent and effective experience every time. Whether you're seeking relief from stress or better sleep, our bisabolol-rich formulations help you unwind and find balance.

Our gummies are a convenient on-the-go option, but for a more customizable experience, try our Buzz Drops™. With just 2.5 mg of THC per dropper, balanced by an equal amount of CBD and a carefully selected terpene profile, they create a gentle, relaxing effect that highlights bisabolol's soothing properties.

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Bisabolol terpene FAQ

Bisabolol (or alpha bisabolol) has many therapeutic benefits. It’s a common active ingredient in skin care products with potent anti-inflammatory and soothing properties. This oily liquid terpene is also found in cannabis plants, where it enhances the overall experience by providing anti-inflammatory, analgesic, and antimicrobial properties.

Bisabolol also shows potential in treating neurodegenerative diseases, offering neuroprotective effects that can support cognitive health. Its sweet aroma and gentle action are a welcome addition to both cosmetic and cannabis products.

Borneol is the terpene most commonly associated with a body high, offering strong analgesic properties. This terpene is often found in hybrid cannabis strains that combine the uplifting effects of sativas with the relaxing, body-focused properties of indicas. Borneol also contributes to the anti-inflammatory and antimicrobial activity of cannabis. Its role in the entourage effect further enhances the therapeutic potential of cannabis products.

Bisabolol is generally safe and widely used in cosmetics, especially in skin care products to treat skin inflammation and dry skin. Those with sensitive skin or allergies to chamomile flower or candeia tree might experience mild irritation or contact dermatitis.

While bisabolol boasts numerous pharmacological properties, make sure to use it in proper concentrations to avoid potential adverse effects such as eye irritation or gastrointestinal discomfort when ingested in large amounts.

Limonene is the terpene most associated with euphoric effects. This terpene is found in cannabis strains with complex terpene profiles. It is known for its sweet, citrusy aroma that uplifts the mood.

Limonene’s strong anti-anxiety and mood-enhancing properties make it a favorite in strains that provide an energizing and emotionally balancing experience. In hybrid strains, it synergizes with other terpenes and cannabinoids to enhance the overall cannabis experience.

While most terpenes are safe, a few such as pulegone and safrole can be toxic, especially in high concentrations. Pulegone, found in pennyroyal and sometimes in cannabis, can cause liver damage, while safrole, found in sassafras, is a known carcinogen. Use terpenes in safe, regulated amounts in cosmetic products, especially those used for topical application.

Linalool is one of the best terpenes for anxiety relief with strong anti-anxiety and sedative properties. Found in lavender, German chamomile, and cannabis plants, linalool is often used in topical application products to reduce stress and improve sleep. This terpene’s sweet aroma also contributes to its calming effects. It works by modulating the nervous system and calming the mind and body. This makes it a popular choice in cannabis strains aimed at providing relaxation and emotional balance. 

Bisabolol is not the same as chamomile, but it is a key active ingredient found in chamomile essential oil, particularly in German chamomile (Matricaria chamomilla). Bisabolol is a terpene with numerous medicinal benefits, including anti-inflammatory, antimicrobial, and antifungal activity. It has calming and soothing properties. While chamomile is a plant composed of many chemical compounds, bisabolol is the specific compound responsible for a wide range of its therapeutic effects.

Bisabolol is known for its soothing and calming effects, making you feel relaxed and relieved from stress. Its anti-nociceptive and anti-inflammatory activities alleviate chronic pain such as arthritic and neuropathic pain, providing a sense of comfort and ease. Bisabolol's ability to inhibit inflammatory processes contributes to its calming effect on the body, helping reduce anxiety and promoting a general sense of well-being. 

Bisabolol is soluble in oil. Because of this property, it is a common ingredient in cosmetic industries. Its oily liquid form allows it to blend well with other cosmetic ingredients, enhancing its effectiveness in treating skin conditions such as dry skin, inflammation, and fungal infections.

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Resources

Gadotti, V. M., Huang, S., & Zamponi, G. W. (2021). The terpenes camphene and alpha-bisabolol inhibit inflammatory and neuropathic pain via Cav3.2 T-type calcium channels. Molecular Brain, 14(1). https://doi.org/10.1186/s13041-021-00876-6

Laws III, J. S., Shrestha, S., & Smid, S. D. (2022). Cannabis terpenes display variable protective and anti-aggregatory actions against neurotoxic β amyloid in vitro: Highlighting the protective bioactivity of α-bisabolol in motorneuronal-like NSC-34 cells. NeuroToxicology, 90, 81-87. https://doi.org/10.1016/j.neuro.2022.03.001

Hanuš, L. O., & Hod, Y. (2020). Terpenes/Terpenoids in Cannabis: Are They Important? Medical Cannabis and Cannabinoids, 3(1), 25-60. https://doi.org/10.1159/000509733

Further reading

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How do edibles relieve sciatic pain?

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