What is humulene?

Oct 03, 2024The nama Team
What is humulene? by namaCBD

Humulene gives many hybrid cannabis strains their earthy scent and offers several therapeutic benefits. This cannabis terpene reduces inflammation, suppresses appetite, and even fights certain types of cancer cells.

The rich terpene profiles of hybrids include humulene and contribute to balanced effects. This blend offers a tailored experience, without indica-induced couch-lock or sativa jitters.

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What are humulene’s effects?

Humulene is a sesquiterpene and an isomer of another terpene, beta-caryophyllene. This means that humulene has the same molecular formula (C15H24) as caryophyllene but a different structural arrangement of atoms, which results in distinct properties and effects. 

In cannabis, hops, sage, ginseng, and some conifers, humulene contributes to the plant's defense mechanisms and aromatic profile. It also helps shape the overall effects and aroma of cannabis strains.

Here are ten ways humulene affects you:

  1. Appetite suppression: THC is known for stimulating appetite (the so-called “munchies”), but humulene might have the opposite effect. Some users report feeling less hungry after consuming humulene-rich strains. This could be why certain cannabis varieties don't give you the urge to raid the fridge.
  2. Relaxation: Strains high in humulene are relaxing and contribute to a chill, unwinding feeling. While it doesn't directly cause relaxation, such as Delta 9 THC and CBD, it often works with other compounds to promote a mellow mood. 
  3. Contribution to the entourage effect: Humulene plays a part in the entourage effect, a phenomenon where cannabinoids, terpenes, and other cannabis compounds work together and enhance each other’s properties and benefits. It may modify how THC and CBD interact with your body's receptors, altering or amplifying their effects.
  4. Anti-inflammatory effects: Humulene calms your body's inflammatory response. These properties could help people dealing with inflammatory diseases and ease symptoms in everything from arthritis to gut issues.
  5. Pain relief: Working alongside other cannabis compounds, humulene contributes to the pain-reducing effects of cannabis
  6. Sedation: Humulene contributes to a gentle, calming effect that helps with relaxation and sleep. If you're looking to unwind after a long day or ease into a restful night, strains rich in humulene are what you need.
  7. Mood: Humulene may contribute to a balanced, positive mood. While not euphoric like THC, it works with other cannabis compounds to promote a sense of contentment and clarity. Humulene can ease stress without cognitive impairment.
  8. Antibacterial potential: Some studies suggest humulene has antibacterial properties. It damages bacterial cell membranes and boosts the effects of other antibacterial compounds.
  9. Anticancer properties: Humulene may inhibit tumor growth in some cancer cells. A 2022 Chinese study shows that, in synergy with another minor terpene called sclareol, humulene can fight pancreatic cancer cells by triggering cell death and stopping cancer spread. They also hinder the development of key proteins in cancer cells, which slows tumor growth in lab tests and live animals. 
  10. Allergy relief: Some research points to humulene having antiallergic properties. It fights stomach irritation and allergic reactions by blocking histamine release from mast cells and ramping up protective factors in your gut lining.

The best way to experience the therapeutic effects of humulene is with our hybrid gummies and THC-infused drinks, which deliver a smooth balance of cannabinoids and terpenes. With no more than 10 mg of THC per serving, our edibles offer a controlled, enjoyable experience.

Start with 5 mg of THC in our Relax Plus gummies. Balanced out by cannabidiol (CBD) and a diverse array of terpenes including humulene, these delectable treats offer a calm, soothing experience.

“I take a half of a gummy in the morning, and it makes me calm and able to handle whatever comes my way. I will continue to order this wonderful product.”

Tina M.

What is the flavor profile of humulene?

You can recognize humulene for its earthy and woody aroma. You'll likely notice a subtle bitterness upfront, followed by warm, spicy notes that linger on your tongue. It's similar to the flavor you might get from chewing on a pine needle or a hop flower. 

There's also a slight peppery quality to it, almost like a mild version of black pepper, but not as sharp. Some people pick up hints of a herbaceous, basil taste. The overall effect is a robust, natural flavor that's not overpowering but noticeable.

What does humulene smell like?

When you take a whiff of humulene, you'll likely be reminded of a forest after rainfall. It has a strong, pine scent, similar to fresh hops or sage. There's also a spicy smell, somewhat like a mild black pepper or coriander. 

The overall effect is a rich, natural fragrance that's grounding and refreshing. This distinctive aroma contributes significantly to the complex scent profile of cannabis strains. 

Cannabis strains high in humulene

Humulene is found in sativa and indica strains, but it’s one of the most abundant terpenes in hybrid varieties. Hybrids offer a balanced experience because they blend the best traits of both sativa and indica, boosted by the therapeutic benefits of humulene for a well-rounded experience. 

Here are six hybrid cannabis strains with a high humulene content:

  1. GSC (formerly Girl Scout Cookies)
  2. Gelato
  3. Sour Diesel
  4. White Widow
  5. Sherbet
  6. OG Kush

With nama™, you don't have to choose between strains. Our products combine the best of both worlds and the balanced ratios of cannabinoids and terpenes from hybrid varieties. You get a well-rounded experience that captures the full potential of cannabis, without having to worry about selecting the perfect strain every time.

Our Energy Delta 9 gummies combine 2.5 mg of THC and 5 mg of CBD to deliver the ideal balance for focus and clarity. Packed with humulene and other soothing terpenes such as myrcene and linalool, these gummies provide an energizing boost while keeping you grounded and calm.

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Potential side effects of humulene

Humulene is safe when consumed in typical amounts found in foods and cannabis, but it can cause side effects in high concentrations. These side effects are mild and can be different from person to person. 

Here are some potential side effects:

  • Skin irritation (when applied topically)
  • Allergic reactions in sensitive individuals
  • Gastrointestinal discomfort
  • Headaches
  • Dizziness
  • Nausea
  • Interaction with certain medications

Always consult a healthcare professional before using products high in humulene, especially if you have existing health conditions or are taking medications.

You don't need to worry about side effects with our microdosed THC gummies because they stay below the psychoactivity threshold and are gentle to your system. They offer all the benefits without overwhelming effects.

Experience the balanced effects of our hybrid edibles

Looking for hybrid cannabis products rich in beneficial terpenes? nama™ has you covered. We specialize in premium cannabis edibles that deliver balanced effects. Our gummies and THC-infused drinks combine high-quality, hemp-derived extracts with calming terpenes to provide a soothing, consistent experience. Whether you’re seeking stress relief or a gentle unwind, our humulene-rich formulas offer a well-rounded cannabis experience.

For an easy, on-the-go option, try our delicious THC gummies. Or, for a chill experience, infuse your favorite drink with our Buzz Drops™. Our low-dose liquid drops contain just 2.5 mg of THC and CBD per dropper, balanced by humulene and other beneficial compounds for a relaxing effect.

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Humulene terpene FAQ

Humulene is not specific to sativa or indica strains. It is a common terpene found in indica and sativa-dominant strains. This organic compound is also present in plants such as hops plant and Cordia verbenacea (wild sage) where it contributes to the distinct herbal aromas. Hybrid cannabis strains rich in humulene offer health benefits because of their soothing, analgesic, and anti-inflammatory properties.

Humulene's function in enhancing your cannabis experience is tied more to its anti-inflammatory and appetite-suppressant effects rather than contributing directly to euphoria or a heightened high. While it doesn't have psychoactive effects like THC, its presence in cannabis balances the overall profile of cannabinoids and terpenes, which gives you a more nuanced, well-rounded experience. Users can enjoy the beneficial effects of cannabis without excessive appetite stimulation.

Humulene does not cause anxiety and is one of the more calming terpenes in cannabis. Its anti-inflammatory and relaxing properties may even alleviate anxiety and balance the overall effects of the cannabis strain. While it doesn't have the same sedative effects as other common terpenes such as linalool, humulene’s relaxing notes contribute to a soothing experience, especially in hybrid cannabis strains.

Humulene is not known for causing sedation or promoting sleep directly. Unlike terpenes such as myrcene and linalool, which have well-documented sleep-promoting properties, humulene provides more calming and anti-inflammatory effects rather than strong sedative properties. While it can help with relaxation, it is not the terpene you would turn to if you're specifically seeking a sedative effect to combat insomnia.

Humulene is not a sedative. While it provides calming effects and has anti-inflammatory benefits, its properties aren’t sedating in nature. Humulene is more commonly known for its therapeutic benefits for inflammatory conditions (such as inflammatory bowel disease and arthritis) rather than directly inducing sleep or deep relaxation. 

Humulene is not psychoactive—it does not contribute to the psychoactive effects or the "high" associated with cannabis. Its primary function in cannabis is to provide anti-inflammatory properties and help balance the terpene content in hybrid strains.

Limonene is one of the most euphoric terpenes. It provides uplifting and mood-enhancing effects and as such can be found in sativa-dominant hybrid strains where it contributes to the "feel-good" sensation. Its distinct citrus aroma and medical benefits, including anti-anxiety and stress relief, make it a popular choice for those seeking an energized, euphoric experience.

Myrcene is one of the most sedating terpenes in cannabis, known for its effects to induce deep relaxation and sleepiness. It is a predominant terpene in many indica strains, where it contributes to the "couch-lock" effect. Myrcene’s chemical formula and strong herbal aromas also make it a key player in cannabis products used for managing chronic pain and sleep disorders.

Pinene contributes to an uplifting and giggly high when combined with other cannabinoids and terpenes. While not solely responsible for causing laughter, when present in hybrid cannabis strains, pinene enhances the experience and promotes a light, happy mood. This terpene also has therapeutic potential in a wide range of medical conditions, such as reducing anxiety and improving airflow.

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Resources

Chassagne, F., Samarakoon, T., Porras, G., Lyles, J. T., Dettweiler, M., Marquez, L., Salam, A. M., Shabih, S., Farrokhi, D. R., & Quave, C. L. (2021). A Systematic Review of Plants With Antibacterial Activities: A Taxonomic and Phylogenetic Perspective. Frontiers in Pharmacology, 11, 586548. https://doi.org/10.3389/fphar.2020.586548

Kang, Y., Wang, X., Wei, X., Li, D., Gan, L., Jin, J., Wu, R., Wu, P., Sheng, Z., Zhang, K., Goodin, S., Xu, X., & Zheng, X. (2022). Synergistic inhibitory effect of α-humulene and sclareol on human pancreatic cancer cells. Journal of Functional Foods, 89, 104958. https://doi.org/10.1016/j.jff.2022.104958

Yeo, D., Hwang, S., Song, Y., & Lee, H. (2021). Humulene Inhibits Acute Gastric Mucosal Injury by Enhancing Mucosal Integrity. Antioxidants, 10(5), 761. https://doi.org/10.3390/antiox10050761

Further reading

Are hybrids uppers or downers?

Our THC gummies that give you energy

THC drinks vs edibles

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How does the hybrid weed trigger the entourage effect?

Indica vs sativa vs hybrid: what you need to know

Side effects of hybrid cannabis strains

What is hybrid weed good for?

The best THC microdosing amounts

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